Let G be a graph, for any real 0≤α≤1, Nikiforov defines the matrix Aα(G) as Aα(G)=αD(G)+(1−α)A(G), where A(G) and D(G) are the adjacency matrix and diagonal matrix of degrees of the vertices of G. This paper presents some extremal results about the spectral radius ρα(G) of the matrix Aα(G). In particular, we give a lower bound on the spectral radius ρα(G) in terms of order and independence number. In addition, we obtain an upper bound for the spectral radius ρα(G) in terms of order and minimal degree. Furthermore, for n>l>0 and 1≤p≤⌊n−l2⌋, let Gp≅Kl∨(Kp∪Kn−p−l) be the graph obtained from the graphs Kl and Kp∪Kn−p−l and edges connecting each vertex of Kl with every vertex of Kp∪Kn−p−l. We prove that ρα(Gp+1)<ρα(Gp) for 1≤p≤⌊n−l2⌋−1.