Introduction: Diabetes Mellitus is a pathology produced by an increase in glucose levels at the blood level, a phenomenon mediated by environmental and genetic factors. This rise in blood glucose levels may be due to a failure in the production, either partial or absolute of insulin, as well as a loss of insulin sensitivity by the tissues. Since diabetic patients only respond to insulinization, and are mostly thin, these canines can have insulin resistance, without developing intolerance to glucose or diabetes. Objective: The objective of this work was to evaluate insulin resistance through the HOMA mathematical model in patients with different body conditions. Methods: Insulin levels were determined through IRMA assay and statistical analysis used X2 test and ANOVA analysis of variance. Results: ANOVA analysis of variance between the groups did not show statistically significant differences between the normoglycemic HOMA group of the obese and normal weight patient, as well as between the diabetic and normal weight HOMA group. The X2 correlation index did not show a significant association between body condition and the altered HOMA index, (X2 = 3.056; p = 0.08). Insulin levels were higher in obese than normal-weight patients, although this difference was not statistically significant (F = 1,004; p = 0.394). Conclusion: The study carried out did not show significant differences in the HOMA levels associated with increases in their body condition, which could be related to a higher state of insulin deficiency over the state of insulin resistance.