The study was undertaken to identify environmental determinants that favor the presence of Pintomyia longiflocosa in a cutaneous leishmaniasis region of Tello, Huila. The abundance pattern was determined by using CDC light traps from 18:00 to 6:00 for two nights on a monthly basis, showing peaks of high abundance in the last month of the dry season. 30 environmental factors were determined in situ and from climatological stations. The environmental determinant that most favors the presence of P. longiflocosa is the average temperature 15 days before sampling, which can condition the development of the life cycle in the immature phase of the insect vector, promoting the increase in the emergency rate of adult individuals. The results of this study help to better understand the biology of P. longiflocosa and they are a tool for the design of measures to prevent and control cutaneous leishmaniasis.