Abstract Energy saving measures, in the design air conditioning systems, are crucial in the development of energy schemes with rational energy consumption. Traditionally, integrated buildings systems have been assessed individually to optimize the energy performance, however they have different parameters that affect energy performance that demands the use of detailed analysis using dynamic simulation. This paper is focused on compare an air conditioning system to be implemented in educational buildings in warm-climate, considering energy schemes provide for a constant air volume (CAV) flow system with a water chiller, while the other integrates a variable refrigerant flow (VRF) system. Adding in each case dedicated outdoor air System (DOAS) units. Energy consumption achieved by each AC system is obtained considering the configuration achieving energy savings of 40% of the annual electricity demand for cooling. Finally, the use of DOAS represents an increase of 20% of total electricity consumption.