This data article presents set-up and input data files to model a surface river plume through curvilinear nested grid in double-way mode. The hydrodynamic modelling in river deltas with intense transport processes and complex bathymetry such as the Magdalena River delta, requires a mesh grid that ease the natural river discharge into the ocean. The aforementioned may be challenging due to the numerical scheme and stability restrictions of the numerical models that difficult having efficient and effective validated simulations. This dataset files are a reference to perform analysis of the hydrodynamic river deltas, meaningful for optimizing time and resources, easing the planning of measurement campaigns what reduce risks of the personnel and instrumentation during equipment deployment and field work .The application of the set-up and input data files of this data article is shown in Rueda-Bayona et al. [1].