This article analyzes the role performed by the police codes related to harlotry issues in the Department of Atlantico. Harlotry was conceived as a public health issue and as a result it can be seen how the regulation system was transformed and adapted to new challenges generated by the local society. Likewise, in collaboration with the press we pursued the image created around women practicing prostitution and how these ideas encouraged female’s spatial exclusion promoted by Law. Hence, we conclude that prostitution was perceived as the main cause of venereal diseases and as a consequence it led to severe regulations of harlotry.