The aim of this study was to estimate brain radiation dose to the main operator during interventional radiology procedures. Occupational brain doses from 19 interventional procedures were measured using thermoluminiscent dosimeters and an anthropomorphic RANDO woman phantom simulating a main operator. Results show that, interventional radiologists may receive minimum and maximum brain doses per procedure of 0.01 mGy (left temporal cortex) and 0.08 mGy (temporal lobe cortex), respectively. A radiologist who works without movable shielding devices during procedures and has a typical workload (for example 500 procedures per year), might exceed the new dose threshold of 0.5 Gy for circulatory disease in the brain working 12.6 years of his career.