There are no studies that allow a joint diagnostic or therapeutic intervention for the treatment of fatty liver and urolithiasis, perhaps because it is not known if there is an association between these 2 diseases. We aimed to identify a relationship between renal lithiasis and fatty liver disease by examining for common factors that could be used to reduce their incidence and complications. Our study supports the association of fatty liver and urolithiasis. Given the increase in frequency of these 2 diseases, we believe there is a common pathway within the malabsorptive and metabolic syndromes, thus leading for a new field of research to find a mechanism that allows timely interventions.