The pharmaceutical industry is now a valuable global health element. The manufacture of medicines and the cleaning of equipment, generate wastewater with emerging pollutants of difficult elimination with traditional treatments, producing environmental impacts on the ecosystems. The following study analyses ozone treatment in the wastewater of the pharmaceutical industry. A review of the scientific literature is made on the wastewater of the pharmaceutical industry, the implementation of traditional treatments, the environmental impacts caused by discharges from that industry, and specifically on the implementation of ozone to remove pharmaceutical waste from water bodies. It was concluded that the ozone treatment is efficient in the removal of pharmaceutical compounds, especially anti-inflammatory, antibiotics and estrogen.