The present research study presents the results of the aerodynamic analysis of a USB AERO aircraft using computational fluid dynamics (CFD) in operational conditions of cruise flight at an angle of attack of 3.5 degrees. The ANSYS FLUENT computational tool was used, with which the lift, drag and longitudinal momentum coefficients were determined. Additionally, the aircraft was analyzed at different angles of attack in order to determine aerodynamic characteristics such as the highest lift coefficient and the loss angle, in addition to establishing the maximum aerodynamic efficiency.