Emerging pollutants are compounds of increased environmental importance and, as such there is interest among researchers in the evaluation of their presence, continuity and elimination in different environmental matrices. The present work reviews the available scientific data on the degradation of emerging pollutants, mainly pharmaceuticals, through ultrasound, as an advanced oxidation process (AOP). This study analyzes the influence of several parameters, such as the nature of the pollutant, the ultrasonic frequency, the electrical power, the pH, the constituents of the matrix and the temperature of the solution on the efficiency of this AOP through researches previously reported in the literature. Additionally, it informs on the application of the referred process alone and/or in combination with other AOPs focusing on the treatment of domestic and industrial wastewaters containing emerging pollutants, mainly pharmaceuticals, as well as on the economic costs associated with and the future perspectives that make ultrasound a possible candidate to solve the problem of water pollution by these emerging pollutants..