In this paper we present an optodigital protocol for the compression of 3D dynamic scenes recorded with an off-axis Fresnel holographic system. The compression protocol involves optical scaling, sampling with binary masks, and multiplexing of the optical field data obtained after a filtering process applied to Fresnel holograms. Volume reduction of up to 93.71% and a 16-fold decrease in the transfer time are achieved. Virtual-optical reconstruction is performed for different values of the parameters involved in the compression protocol. The correlation coefficient is used as a metric to measure the loss caused by the volume reduction process. Furthermore, we show that a high level of lossy compression can be achieved with this protocol, with better reconstruction quality than the MPEG-4 video compression technique. Finally, we perform the experimental reconstruction using a holographic projection system based on a phase-only spatial light modulator, thus highlighting the potential of our proposal.