Introduction: The aim of this article is to analyze inequalities in the practice of physical activity for enhancing physical conditions or for doing sports, generated by different social, geographical and demographical determinants, as well as some of their interactions. Development: A quantitative analysis of secondary data was conducted. The source is the National Survey of Risk Factors, based on a probabilistic sample of urban households in Argentina, in 2009. Firstly, it is presented a escriptive bivariate analysis and, secondly, binary logistic regressions to test hypotheses on the net effect of different independent variables are shown and incorporated interactions within them to observe their intersectionality. Conclusions: Findings show the importance of considering an intersectional approach to account for the multiplicative nature of inequalities in the practice of physical activity, which most used multivariate models fail to show.