This study focuses on the need for the support that is required from the Information and Communication Technologies to the psychotherapeutic processes related to PTSD, which are treated based on the internationally standardized clinical diagnoses in the DSM- V and CIE 10, These are dictated by expert psychotherapists. Immersive virtual reality (IVR) is today a technology that supports the implementation of interactive applications in psychological rehabilitation, becoming very important in exposure therapies as support in PTSD treatment protocols, supported by the techniques of user-centered design for building applications.