The investigation of human rights violations in Colombia, which include disappearances, massacres, homicides and extrajudicial executions, faces important obstacles and challenges that affect the clarification of facts, the determination of responsibilities and integrated reparations for victims, placing Colombia in third place on the Global Impunity Index. Although this dishonorable position is a direct result of the structural problems of the country's political and justice system, it is also related to the continued use of "traditional" contextual and forensic investigation methods. This chapter presents the actions proposed and promoted by EQUITAS for the documentation, approach and integrated analysis of cases involving serious violations of human rights based on an interdisciplinary perspective that includes methodological and technological innovations. To achieve this, specific case studies are discussed. In Colombia, state authorities have favored search strategies based on witness and perpetrator testimonies as the main source of information used to locate clandestine graves.