The purpose of this work is to characterize the process of natural neuronal death associated with brain aging in healthy subjects by characterizing local relationships in nuclear magnetic resonances. The whole method focuses on describing local neighborhoods with a texture descriptor, specifically the Linear Binary Pattern invariant to rotation, aiming to capture local tissue relationships by clustering this texture descriptor in brain regions previously parcelled. This approach has been tested in a group of control subjects extracted from the ADNI database project, dividing the experimental group after subjects' chronological age. Results show differences concentrated in certain regions, i.e., the caudate, the hippocampus, and the thalamus, all of them usually reported as deteriorating with ageing process.