Lead causes neurological and other adverse effects that in many cases are irreversible, especially among children. According to the Global Burden of Disease, lead exposure causes 13.936.400 Disability Adjusted Life Years (DALY) globally; in Colombia, lead accounts for 95.285 DALY and is one of the 10 main causes of death in all age groups. In spite of this, Bogota lacks of a biomarker´s surveillance system to detect early cases and only those with clinical features are currently being treated. Threshold for blood lead levels are set in 5 µg/dl for children and 38 µg/dl for adults. Aim of the study was to determine the degree of association between blood lead levels over threshold and presence of clinical features in Bogota population. 401 persons were selected by simple random sampling; each of them underwent a thorough clinical examination by general practitioner and blood testing. Lead determination was carried out by atomic absorption spectrophotometry at 253 nm. A narrative description of clinical features of population with increased lead levels is presented. Strength of association between lead levels and clinical features by kappa statistics was considered good (?>0.6), fair (? 0.2-0.6) or poor (?<0.2). Neurodevelopmental disorders were the clinical features most commonly observed in children under-16. Clinical findings for adults were mainly related to cerebellar syndrome (n=20). Cases with increased lead levels are mostly located in the southeast part of the city, characterized by inadequate housing, low socioeconomic status and informal work. Prevalence of clinical lead poisoning in children (18%) was lower than percentage with elevated blood lead levels (38%) (?=0.05). Meanwhile clinical suspected cases in adults were 21%, but only 1% surpassed lead threshold (?=0.01). Clinical features and laboratory measures are poorly correlated. A new approach for chronic lead exposure surveillance is needed, especially in vulnerable population such as children.