A vastly quantity of scientific research were made through the last decade on the development of a great number of drugs to treat complex diseases like HIV or cancer.However, the long-term treatment with these drugs is actually associated with appearance of idiopathic syndromes that carry to stop the treatment.In this sense, we sought to perform a study of two novel promissory drugs.The first one was performed from a methodological study of intermediaries came from modified amino acids to obtain a hybrid compound that would act as a protease inhibitor against HIV-1.The second one was performed from the study of 1,3,5-triazine ring reactivity, starting from cyanuric chloride and the analysis of reactions with diverse nucleophiles.Our results showed that for the hybrid synthesis, a difficulty on purification impede to obtain all the intermediaries so that molecule was not obtained.The results for triazines, were promissory due to theoretical studies let us to determine possible biological activity and was observed that there are more conditions that must be evaluated on cyanuric chloride reactions.In addition, the proposed derivatives were synthetized and the biological activity was assessed.Biological outcome showed that triazine have a direct interaction with different cultured cancer cells.Finally, as a part of our reactivity studies about triazines we synthetized triazine-BODIPY derivatives in which, we observed that the extension of the conjugation for 1,3,5 triazine ring modified photophisical characteristics of the fluorophore.Thus, our results suggested that triazines could have promissory properties that must be explore in further studies.