Abstract Traditionally a limb that has suffered a fracture, rupture or dislocation is immobilized with plaster, a procedure that generates discomfort in the patient to take a shower, besides producing excessive itching and sweating, stimulating the growth of the bacteria and leading to an odorous form, unhygienic and difficult to keep clean of treatment. On the other hand, if the plaster remains for a long period, it can cause injuries in joints and ligaments. This project describes a methodology of manufacturing a prototype of orthosis for upper limb printed in 3D, through additive manufacturing and reverse engineering, technology that is presented as an excellent alternative to solve the problems of traditional plaster molds. The model of the orthosis is obtained through the Meshmixer software and the structural viability of the design is studied using methods of finite element analysis and biomimetics, to guarantee the best possible mechanical properties. The realization of this work provides a custom-made prototype orthosis, a more comfortable, hygienic and aesthetically pleasing solution, which in turn allows the reduction of the time of use of the plaster molds.