Abstract Commercial Portland cement is the most used construction material in the world, due its durability, versatility and economy generated in civil works, which follows a growth trend; however, a large amount of energy is required for its production, which generates a large amount of greenhouse gas emissions and air pollutants. Consequently, a large part of research has focused on mitigating these effects by partially replacing supplementary cementitious materials. Therefore, this research aims to evaluate the performance of commercial cement paste, partially replacing it with fly ash and blast furnace slag, characterized by scanning electron microscopy, X-ray fluorescence, surface area to establish variations of setting times and heat of hydration in hardening process. The results established that fly ash and blast furnace slag didn’t generate sufficient capacities to develop stable cementation reactions and therefore higher strengths, due to their compositions surface area and the high content of alternative cements present in the commercial Portland cement since its manufacture. Nevertheless, the fly ash and blast furnace slag are alternatives in mitigating the environmental effect generated by commercial cements.