Objective: To determine clinical characteristics in newborns with pulmonary or extra-pulmonary disease who undergo successful EXIT procedures at the Fetal Therapy Units of two reference centers in Bogota, Colombia. Methodology:Descriptive case series study.Cases were defined as singleton pregnancies, with pulmonary or extra-pulmonary pathologies which caused obstruction in the fetal airway.Results: Between 2006 and 2016, 54 patients underwent EXIT procedures.Results from prenatal diagnostic testing revealed the following: 27 patients (50%) were diagnosed with diaphragmatic hernias, 15 patients (28%) with cystic adenomatous malformation, four patients (7.4%) with hydrothorax, three patients (5.5%) with bronchopulmonary sequestrations, three patients (5.5%) with cervical masses, one patient (1.8%) with micrognathia, and one patient (1.8%) with a Bronchogenic Cyst (QB).The average gestational age during the EXIT procedures was 37.2 ± 2.54 weeks (range 27-40 weeks).During ultrasound monitoring, 39 (61.1%) cases of fetal complications were reported, eight (14.8%)maternal complications during pregnancy, and seven (13%) maternal surgical complications during the EXIT procedure.Average time of EXIT procedures was 10.8 ± 5.29 minutes (range 5-40 minutes) with an average hospital stay of 9.1 ± 8.5 days (range 1-39 days).The neonatal mortality rate was 60.3% (32/53 patients). Conclusion:The EXIT procedure guarantees an effective transition into the postnatal environment, considerably increasing the chances of survival for the fetus by re-treating a potential emergency into a controlled state.