Extra-auditive effects of increased noise perception include anxiety, irritability, and sleep disorders and undermine health and quality of life in affected communities. Currently, maximum permissible immission noise levels (Leq) are: residential areas (day 55 dB, night: 45 dB), commercial areas ( day: 70 dB, night: 70 dB) and institutional areas (day: 55 dB, night: 45 dB). Aim of the study was to know the impact of immision noise levels on neuropsychological health and quality of life of Bogota adult population and review the noise threshold of the different land use types. A cross sectional design was applied. In five different zones of Bogota with specific noise patterns, 470 participants were selected through two stage random sampling. Day and night time immission noise levels were measured. Neuropsychological effects and socioeconomic factors were assessed through a perception survey. Noise measurements were performed according to Bogota standard procedures. Statistical analysis include logistic regression to determine associate factors of neuropsychological symptoms and lineal regression to establish mean thresholds of noise adverse effects. More than a third of the population referred health effects associated with noise (35%). Prevalence of neuropsychological symptoms were irritability (28%), headache (27%), fatigue (22%) and insomnia (21%). Multivariate analysis showed that sleep disorders are associated with night time noise levels in residential land use (ß=0.03, p<0.05). Geometric mean perception thresholds found were: commercial zone ( day Leq: 64dB, night Leq: 60 dB), institutional zone (day Leq: 55 dB, night Leq: 45 dB ) and residential zone (day Leq: 53 dB, night Leq: 42 dB). Bogota has a high burden of disease due to noise, particularly during night time in residential areas. Sleep disorders increase in 3% for each one extra dB in residential areas. Findings suggest the necessity of adjusting noise thresholds to more restrictive levels.