Introduction. Population with diabetes mellitus are more vulnerable to unusual increases and fluctuations of temperature and relative humidity due to their difficulties to control plasma glucose level in presence of dehydration. Bogota is a city with mild temperatures (15ºC to 21ºC but there has been a sudden change in mean temperature during the last 15 years, with increases ranging from 1º up to 2.2 ºC. The aim of the study was to know the combined effects of increases in temperature and humidity and their impact on the urgent admissions due to the different types of diabetes mellitus.Methods. Through an ecological design we examined the temporal patterns of urgent daily admissions of 7 different ICD-10 diagnoses of diabetes mellitus spectrum and mean temperatures, relative humidity, ground level ozone (03) and particulate matter (PM10 and PM2.5) from 2009 to 2013. We calculate the heat index with Steadman equation as recommended for temperatures below 80º Fahrenheit (<26ºC). Statistical analysis included Spearman rank correlation and Poisson regression models. Results. Diabetic ketoacidosis was the only event correlated to relative humidity (Rho=0,04, p<0,05), mean temperature (Rho=0,05, p<=0,05) and PM10 (Rho=0,08, p<0,05). Regression analysis: diabetic ketoacidosis showed an increase of 2,4% of the cases per unit increase of the heat index (β=0,024, UI 95% 0,005-0,041) and an increase of 4,5% of admissions per unit increase of PM10 (β=0,044, UI 95% 0,028-0,061). Conclusions. Vulnerability to increases in temperature and humidity in a city of mild climate seem not to be distributed equally across diabetes mellitus spectrum. Type I diabetes patients were more prone to ketoacidosis which its plausible because the underlying biological effects. Next research should focus on the effect of socioeconomic status, sex and age on diabetic urgent admissions and also explore the spatial patterns of diabetes spectrum within Bogota.