Electronic tongue-type sensor arrays are devices used to determine the quality of substances and seek to imitate the main components of the human sense of taste. For this purpose, an electronic tongue-based system makes use of sensors, data acquisition systems, and a pattern recognition system. Particularly, in the latter, machine learning techniques are useful in data analysis and have been used to solve classification and regression problems. However, one of the problems in the use of this kind of device is associated with the development of reliable pattern recognition algorithms and robust data analysis. In this sense, this work introduces a taste recognition methodology, which is composed of several steps including unfolding data, data normalization, principal component analysis for compressing the data, and classification through different machine learning models. The proposed methodology is tested using data from an electronic tongue with 13 different liquid substances; this electronic tongue uses multifrequency large amplitude pulse signal voltammetry. Results show that the methodology is able to perform the classification accurately and the best results are obtained when it includes the use of K-nearest neighbor machine in terms of accuracy compared with other kinds of machine learning approaches. Besides, the comparison to evaluate the methodology is made with different classification performance measures that show the behavior of the process in a single number.