A review of the radionuclides produced in nuclear reactors and their applications as radiotracers in hydrology, agriculture, industry, medicine, the environment and research in general are presented, both in Latin America and those produced in Colombia since 1965 with the Research Nuclear Reactor IAN-R1, so that under that view it is possible to reactivate the production of radionuclides in the country as 198Au, 24Na, 32P and 82Br.