One of the benefits of collaborating in an interprofesional team is the exchange, and the acquisition of knowledge, skills and operational strategies alongside this community. Here, we share an example and an analogy from the medical field: A biomedical engineer, from a simulation center, who has the task of preserving the functionality, integrity and aesthetics of the simulators and the equipment, acquires a role similar to that of a doctor who seeks strategies that focus on maintaining a healthy population. The following is a review of our experience in the Centro de Enseñanza por Simulación de Posgrado (CESIP) of the National Autonomous University of Mexico (UNAM). It should be noted that none of the strategies stated here can be considered as a reference “of excellence” for the operation of a simulation center, due to the great number of particularities in each of them. Finally, we are convinced that sharing our experience may be useful for other centers, especially due to the lack of information available. Keywords: Simulators, maintenance, biomedical,conservation.