Suicidal behaviors occur mainly during adolescence and when people face highly demanding circumstances. The objective of this work was to characterize the prevalence of suicidal behavior in adolescents of the High Threat Zone of the Galeras Volcano -ZAVA-, and to establish its association with demographic and psychological variables. The sample consisted of 154 adolescents enrolled in educational institutions located in the ZAVA, in whom the presence of suicidal behavior, depression, despair, self-esteem, social support and vital events were evaluated. The prevalence for suicidal ideas in the course of life was 17.5%, for plans 6% and for attempts 8%. Suicidal behaviors were related to sex, depression, hopelessness and number of stressful life events. It is concluded that adolescents constitute a population with a risk of autolytic behaviors, demanding actions to face this situation, from a public view of mental health.