A 69-year-old patient who underwent photovaporization of the prostate (PVP) with GreenLight<sup>TM</sup> Laser presented chronic abdominal pain, in the following and after 7 months, an abdominal MRI showed a bladder mass and the cystoscopy revealed an 8 cm of diameter grayish mass of the anterior wall and the dome. Malignancy, infectious, and granulomatous diseases were ruled out. Biopsy showed necrotic tissue and dystrophic calcification (DC) with crystals and Gram-positive cocci, so a transurethral resection was intended failed due to the mass hard consistency and size. The patient was taken to partial cystectomy and the pain resolved. DC is defined as inappropriate deposits of calcium phosphate salts in previously damaged tissue by different forms of trauma: burns, radiotherapy, and surgery. We suggest the DC process is linked to a previous thermal lesion of the bladder during PVP and believe future studies of association can be relevant.