The objective of this study was to evaluate the acute cardiac response after performing an exercise session with vascular occlusion in elderly adults (EA). Twenty-two volunteer participants underwent the experimental protocol of dynamic manual grip exercise with 30% occlusion pressure (OP), after recording the baseline values and resting systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate (HR). All measures were taken in basal conditions and between 5 and 30 minutes’ post-occlusion. At the end of the protocol, there was a significant reduction in SBP and HR at 15 ', 20' and 25 '(p <0.05) and for DBP at 10' and 20 '(p <0.05).). The acute effect of exercise with vascular occlusion generates a significant reduction of SBP, Basal Diastolic Pressure (BDP) and HR up to 25 minutes’ postcclusion, in the EA analyzed.