This paper studies the problem of scheduling in single-hop wireless networks with real-time traffic, where every packet arrival has an associated deadline and a minimum fraction of packets must be transmitted before the end of the deadline. Using optimization and stochastic network theory we propose a framework to model the quality of service (QoS) requirements under delay constraints. The model allows for fairly general arrival models with heterogeneous constraints. The framework results in an optimal scheduling algorithm which fairly allocates data rates to all flows while meeting long-term delay demands. We also prove that under a simplified scenario our solution translates into a greedy strategy that makes optimal decisions with low complexity.