ImpactU Versión 3.11.2 Última actualización: Interfaz de Usuario: 16/10/2025 Base de Datos: 29/08/2025 Hecho en Colombia
ChemInform Abstract: Synthesis of Novel Polysubstituted (2SR,4RS)‐2‐Heteroaryltetrahydro‐1,4‐epoxy‐1‐benzazepines and cis‐2‐Heteroaryl‐4‐hydroxytetrahydro‐1H‐1‐benzazepines as Antiparasitic Agents.
Abstract Many of the new compounds (II), (III), (V), and (VI), synthesized via an intramolecular 1,3‐dipolar cycloaddition of nitrones derived from O‐allyl‐N‐hetarylmethylanilines (I) or (IV), inhibit significantly the growth of extracellular forms of Trypanosoma cruzi and Leishmania infantum parasites without showing cytotoxicity on Vero and HTP‐1 cells.
