Abstract Benzo[ h ]pyrimido[4,5‐ b ]quinolines ( 3 ) have been synthesized via a regiospecific cyclocondensation reaction between 6‐aminopyrimidines ( 1 ) and 2‐dimethylaminomethylentetralone hydrochloride ( 2 ). The linear structure of the final compounds were determined by nmr measurements, especially by 1 H, 1 H, 1 H, 13 C COSY and DEPT experiments.