Abstract This study addresses the need to exchange clinical records, efficiently and uniform among health institutions (IPS Spanish acronym for Instituciones Prestadoras de Salud), which is generated in clinical care users from using the Hospital Information Systems (HIS). From defining a model for interoperability, with reference to the regulations governing the General System of Social Security in Health in Colombia (SGSSS Spanish acronym for Sistema General de Seguridad Social en Salud), the standards to facilitate electronic exchange of clinical information Health Level Seven (HL7) and service oriented architecture (SOA). The model it wasdesigned in two dimensions, on the one hand horizontally would facilitate electronic exchange of clinical information between IPS and on the other side vertically was projected was obtained as they settled components for the exchange of healthcare and administrative records the SGSSS different actors, in this case with the health Promotion Companies (EPS Spanish acronym for Empresas Promotoras de Salud) and the Territorial Entities through health secretaries.