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Study of cervical cancer through fractals and a method of clustering based on quantum mechanics

Acceso Cerrado
ID Minciencias: ART-0000199141-98
Ranking: ART-ART_A2

Abstract:

Tumor growth in the cervix is a complex process. Understanding this phenomena is quite relevant in order to establish proper diagnosis and therapy strategies and a possible startpoint is to evaluate its complexity through the scaling analysis, which define the tumor growth geometry. In this work, tumor interface from primary tumors of squamous cells and adenocarcinomas for cervical cancer were extracted. Fractal dimension and local roughness exponent (Barabási and Stanley (1996)), aloc, were calculated to characterize the in vivo 3-D tumor growth. Image acquisition was carried out according to the standard protocol used for cervical cancer radiotherapy, i.e., axial, magnetic resonance T1 - weighted contrast enhanced images comprising the cervix volume for image registration. Image processing was carried out by a classification scheme based on quantum clustering algorithm (Mussa et al. (2015))combined with the application of the K-means procedure upon contrasted images (Demirkaya et al. (2008)). The results show significant variations of the parameters depending on the tumor stage and its histological origin. © 2019

Tópico:

Gene expression and cancer classification

Citaciones:

Citations: 7
7

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Información de la Fuente:

SCImago Journal & Country Rank
FuenteApplied Radiation and Isotopes
Cuartil año de publicaciónNo disponible
Volumen150
IssueNo disponible
Páginas182 - 191
pISSNNo disponible
ISSN1872-9800

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