This systematic literature review collects and discusses the main needs, expectations, and barriers of people with quadriplegia and caregivers in relation to the self-help devices that are currently used for daily tasks. The major advantages, disadvantages, and challenges of the existing assistive technology are exposed and discussed in order to evaluate whether an existing technology could be combined with others to expand its scope, enhance its performance, or solve its limitations improving the adherence of quadriplegic population to these technologies and enhancing their quality of life.