Scarce is the information that we had until now on the family Hinojosa Granada, branch by feminine through of the illustrious lineage Granada Venegas. However, from the notarial and judicial documentation of the archives of protocols and Royal Chancery of Granada, the biography of this lineage is delineated from its genesis until the biological extinction in the course of a century. The memory of a noble progeny, the life of its members, conflicts and confrontations, objectives pursued, marital strategies, the linking of goods to mayorazgos are reconstructed and recovered from oblivion in order to ensure the continuity of the lineage and its prosperity, purpose that would end in absolute failure.