INTRODUCTION: Stromal tumors account for 1-3% of primary gastric neoplasms. They can occur at any age, but they rarely reach more than 10 cm in size. These rare tumors are called gastrointestinal stromal tumors (GIST's) of lafamilia sarcomas whose classification is still controversial. Surgery is the treatment of choice and its length is determined by tumor size, involvement of neighboring organs and the presence or absence of metastases. In selected cases minimally invasive surgery can be performed with excellent results. We present fifteen cases of gastric GIST whose management was by video laparoscopy. The gastrointestinal stromal tumors or GIST were originally classified as another type of tumor (leiomyoma, leiomyoblastoma, or leiomyosarcoma), due to its histological appearance similar, however, advances in molecular biology and immunohistochemistry have allowed them apart from other gastrointestinal malignancies and define them as a distinct clinical and histopathological entity. GISTs originate from the interstitial cells of Cajal, located in the myenteric plexus of the gastrointestinal wall, represent a rare type of tumor of mesenchymal origin (sarcoma), and is estimated to correspond to 0.2% of gastrointestinal tumors and 20-30% of all soft tissue sarcomas. Its incidence in the reported series is 4-10 cases / million inhabitants / year. It affects men and women in similar proportions, with a median of between 55 and 65 years. MATERIAL AND METHODS: We report 22 cases of laparoscopic resection of gastric GIST are reported, with an average 105 minutes operating time, location gastric body 11 (50%), gastric bottom 5 (24%) gastric antrum 6 (26%). Average tumor size 5cm (1cm-8cm), not was required for en bloc resection, pathology, 70% fusiform, epithelioid 20%, mixed 10%, complications 1 (8%) hemoperitoneum, hospital stay average 4 days. DISCUSSION / CONCLUSION: Is considered the treatment of choice surgical resection, that manages to be complete in most cases. The gastric or intestinal segmental resection should get negative surgical margins, Laparoscopic exploration to detect a possible metastatic commitment peritoneal or liver undetected imagenological do in preoperative evaluation. There reports postulate the possibility of a safe and successful removal of GIST using techniques laparoscopic or combined laparoendoscopic resection.Figure