Background/Aim: Carcinogenesis of electromagnetic fields due to mobile phone exposure is still a matter of controversy. IARC has considered electromagnetic fields in the group 2B as possibly carcinogenic to humans. Aim of this study was to analytically review the recent observational studies that tested the association between mobile phones and brain neoplasms. Methods: Studies from 2010 to 2016 in 9 electronic databases were searched with the following syntax: "electromagnetic fields" OR "mobile phone" AND "brain neoplasm" OR "brain cancer" OR "brain tumours. A total of 6316 abstracts were extracted and after removing duplicates and those that did not fufill the inclusion criteria seven case-control studies were selected; only one cohort study that filled the criteria but was not included because is still ongoing. Assessment criteria were frequency (once a week for at least 6 months), intensity (cumulative exposure >1000 hours), duration (>5 years) and laterality of tumour (ipsilateral o contralateral to the phone's use). Odds ratio was used as a summary measure of association and was represented by forest plots. Heterogeneity was assessed by Q test. Publication bias was tested by Egger and Begg tests. Statistical analysis was carried out in Epidat 3.1. Results: From assessment criteria only the intensity (OR=1.59 UI 95% 1.17-2.16) was statistically significant. Frequency (OR=1.08 UI 95% 0.93-1.26), duration (OR=1.10 UI 95% 0.78-1.56) and ipsilateral phone's use (OR=1.33 UI 95% 0.91-1.91) were not associated to an increased risk of brain tumours. High heterogeneity and publication bias both were observed except for intensity (Q=0.09 p=0.76; Egger=-0.09 p=0.92). Conclusions: The results of this study suggest an increased risk of brain tumours in users with high intensity of use (>1000 hours). However taking into account that our meta-analysis included only case-control studies and due to the complexity of defining the mobile's phone exposure, future meta-analysis must include cohort studies to accurately assess the risk of mobile phones and brain carcinogenesis.