<h3>Background</h3> Chikungunya virus is a Togaviridae family virus transmitted by mosquitoes, which generates febrile syndrome with joint pain. It has been widely studied for the findings of chronic inflammatory polyarthropathy similar to rheumatoid arthritis. In Colombia, an epidemic occurred between 2014 and 2015, which was studied in several cities. International meta-analyses have shown a prevalence of 32.13% in the follow-up cohorts greater than 18 months. At present, this issue has gained a new opportunity due to the appearance of new outbreaks in Italy and France, after 10 years of the first epidemic. <h3>Objectives</h3> To compare the clinical findings of a cohort of patients with Chikungunya in the subacute phase and the chronic phase. <h3>Methods</h3> Follow-up of 70 patients who attended Chikungunya in a Colombian population who were evaluated in person by a rheumatologist, initially at 40 days after the disease and after two years. <h3>Results</h3> The average age of the study participants was 59.88 years, being more frequent in women with 78.6% of the cases. 40% of the cases were older than 65 years, with the older adult population being a representative part of the cases. The history of osteoarthrosis occurred in 11.7% of cases. There was no history of systemic lupus erythematosus. The most frequent symptoms presented at the first visit (outbreak context) were as follows, in order: Joint pain (71.4%), morning stiffness (48.6%), Metacarpophalangeal compression test (51.2%). The most frequent symptoms in the second visit (two years after the outbreak) were: joint pain (74.2%), morning stiffness (21.4%) and metacarpophalangeal compression test (17.1%). At the time of the second visit, the clinical findings were classified by diseases, according to the rheumatologist’s assessment as follows: Post-Chikungunya polyarthropathy (17.1%), Fibromyalgia (10%), Carpal tunnel syndrome (17.1%), Osteoarthritis of knees (32.8), osteoarthritis of distal interphalangeal (20%), painful shoulder syndrome (17.1%), tenosynovitis (18.6%), gout (1.4%), sequelae of fracture of hip (1.4%), lateral epicondylitis (1.4%). 28.5% of the cases had no diagnosis of rheumatological pathology. Of the total cases, only 24.3% (17 people) had symptoms for more than 6 weeks. <h3>Conclusions</h3> Chikungunya virus infection increases the prevalence of joint and extra-articular rheumatological diseases in the Colombian population evaluated. <h3>References</h3> [1] Rodríguez- Morales A, et al. Prevalence of post-Chikungunya Chronic Inflammatory Rheumatism: A Systematic Review and Meta-Analysis2016. [2] Campion E. Chikungunya Virus and the Global Spread of a Mosquito-Borne Disease. NEJM2015. [3] CDC. Chikungunya in Italy2017. <h3>Acknowledgements</h3> Association Colombian of rheumatology The epidemiological research centre, Industrial University of Santander. <h3>Disclosure of Interest</h3> None declared