e14653 Background: Colorectal cancer is the third leading cause of cancer death in the Western world and the fourth leading cause in Colombia, being the East the regions with the highest mortality rates. There are many prognostic factors described in the literature, but the clinical stage is the most important but the pattern of occurrence of this neoplasm has been little studied. Methods: A descriptive study of patients with Colon, Rectum and Anal cancer who attended to Oncólogos del Occidente of eastern Colombia (Caldas, Risaralda, Quindío, and North of Valle) from 1997 to 2013 was performed. Results: 2279 patients were analyzed with 50 % of colon, rectum 41 % and 9% of anal cancer; 56 % female; 38% of 41-60 years old and 43% from 61-80 years, 7% over 81 years old; 41 % in right colon , middle rectum 49 % and 43 % low rectum; 44% localized clinical stage, 43% in advanced stage and 10% metastatic state; Caldas State 34%, Risaralda state 33%, Quindío state 23% and North of Valle state 9%; 93% Urban Area; chemotherapy regimens applied like XELOX 13.4%, 4.4% Capecitabine alone, FOLFOX 4 in 6%, 5-FU as monotherapy in 4% and LF on 45%. The distribution of diagnoses per year was 2% in 1997, 8 % in 2009 increased to 15% in 2013; prognostic factors were Obstruction ( 29%), Ulceration ( 25%) and 30% without any factor; 33% had 12 or more lymph nodes retrieved; 27 % had liver metastases. Conclusions: To our knowledge, this is the first study and represents a report that will reveal the epidemiological profile of this neoplasm in a specific area of Colombia (Coffee Triangle) in order to understand their pattern of occurrence, so subsequent analytic studies should be made based on this work.