In this paper, Computational Fluid Dynamics (CFD) is used to perform a transient analysis of physical variables associated with aerodynamic behavior in unmanned aerial vehicle (UAV). The simulation is used to observe vortex, pressure and turbulence kinetic energy (TKE) with post-processing. These variables facilitate the aerodynamic evaluation in aerial devices. CFD studies are currently being conducted to improve efficiency in a large number of devices such as wind turbines, aircraft and, as in our case, unmanned aerial vehicles. It was observed how the aerodynamic behavior in the Hexacopter varies in time and that there is an impact when using four and two blades in its rotors. In this simulation show the turbulence and variation in the pressure on the structure of the arms, achieving a study to propose future applications that seek the reduction of the overpressure and use of the generated turbulence.