Aim: To determine the relationship between cognitive distortions and the risk of suicide in a sample of Chilean and Colombian adolescents. Methods: This is a descriptive-correlational study, non experimental and transversal. The risk of suicide was assessed with the suicidality scale of Okasha and the cognitive distortions were determined with the Automatic Thoughts Inventory from Ruiz and Lujan. These tests were performed in a sample of Chilean (n = 200; from Alma Mater School) and Colombian (n = 200; educational institution Santa Librada) adolescents between 13 – 18 years-old. Sample was selected through non-probabilistic intentional sample procedure, and the individuals were divided in two groups: with suicide risk and without suicide risk (control). A descriptive analysis of the sample, as well as a comparison of the cognitive distortions between groups was performed. Then, inferential analysis of the data was used to determine the relationship and the intensity between cognitive distortions and the suicide risk. Results: A significant relationship between the cognitive distortions and the suicide risk was found, and the following presented the highest intensity between Chilean and Colombian individuals: Filtration, Interpretation of Though, Polarized Though and Overgeneralization). Moreover, the relationship between the results in Chilean and Colombian adolescents was positive and strong. Conclusion: The cognitive distortions correlate with the risk of suicide in the assessed sample of Chilean and Colombian adolescents. Therefore, the evaluation of these factors will allow to the guidance and improvement of preventive psychotherapeutic interventions.