The purpose of this research was to design strategies for technological innovation for the Institutions that Provide Health Services IPS in Cúcuta. A random sample of eight Institutions was selected and estimated under the probabilistic sampling technique for finite population. The elaboration of the strategies started from an internal analysis. Simultaneously, an external analysis was carried out through a technological mapping of the Institutions to identify the technological gaps through comparisons with the national benchmarks of the health sector in Medellín and Cali. The competitive position that served as the basis for designing technological innovation strategies was determined. The focus of the commitment of the institutions providing health services in Cúcuta should be based on the generation of added value and comprehensive care for the patient, specialized human talent and use of ICT for the provision of services. In conclusion, the high impact factor corresponds to the implementation of new technologies in the provision of healthcare services under the use of ICT tools, to provide comprehensive care to the patient; together with the transfer of technology in biomedical equipment to provide diagnostic services and treatments tailored to the users' needs.