Orbital cellulitis is a condition that represents the main infection of ocular adnexa and orbital tissues.Clinical criteria and tomographic data allow classification of the condition for correct treatment to avoid complications and permanent sequelae, mainly for the patient's vision.It requires adequate and multidisciplinary intervention from the beginning, and it is important to take into consideration that the treatment must consist of systemic antibiotics in all cases and depending on the situation, surgical procedures may be required.The primary management in the treatment should provide an appropriate empirical antibiotic therapy that gives coverage against the most frequently involved microorganisms.It should be started as soon as possible and modified, if necessary, based on the interpretation of the Gram stain, the culture, and the susceptibility of the isolated microorganism.