The present article is the result of reflecting, from social bioethics, on gender conflicts and the need to link masculinities both to gender studies and to social movements and public policies. A genealogy of certain social forces that have invigorated gender studies from the understanding of gender-based violence, public health, food and environmental degradation is presented in terms of differences and bio-problems. From this perspective, there are some challenges that society faces in connecting these understandings and change strategies, when it comes to building a horizon of political action. From public policies, society and academia, it is necessary to continue working on the structural factors that perpetuate violence against women, the legitimization of violence among men and their enrollment in armed groups, as well as the promotion of the exercise of paternity and the ethics of care and their impact on politics and the economy. These topics need to be debated in order to build more egalitarian societies.