Abstract During the last ten years, base metals have become very attractive to the organometallic and catalytic community on activation of C-H bonds for their catalytic functionalization. In contrast to the statement that base metals differ on their mode of action most of the manuscripts mistakenly rely on well-studied mechanisms for precious metals while proposing plausible mechanisms. Consequently, few literature examples are found where a thorough mechanistic investigation have been conducted with strong support either by theoretical calculations or experimentation. Therefore, we consider of highly scientific interest reviewing the last advances on mechanistic studies on Fe, Co and Mn on C-H functionalization in order to get a deep insight on how these systems could be handle to either enhance their catalytic activity or to study their own systems in a similar systematic fashion. Thus, in this review we try to cover the most insightful articles for mechanistic studies on C-H activation catalyzed by Fe, Co and Mn based on kinetic and competition experiments, stoichiometric reactions, isolation of intermediates and theoretical calculations.