We considered several mesoscale pinning/anti-pinning landscapes simulated with the parameter α(T) in the Ginzburg Landau free-energy density in a mesoscopic superconducting square of size L2. We analyzed the effects of the size, local critical temperature, position and number of the pinning/anti-pinning centers on the vortex configurations and magnetic response for several values of the Ginzburg-Landau parameter κ ([1 ≤ κ ≤ 8]). We shown that the fields depends strongly on the local critical temperature, configuration and number of the defects on the sample.