BACKGROUND: The effect of whole body vibration on strength, power and force differences (asymmetries) during the sit to stand (STS) test and isometric strength test assessed with uniaxial force platforms in patients with osteoarthrosis of the knee. OBJECTIVE: To evaluate the effects of whole body vibration on neuromuscular performance and asymmetries in lower limbs in patients with or at risk of knee osteoarthrosis. METHODS: Randomized-Controlled trial with 60 subjects (mean age of 48 years + 14.2) with diagnosis or at risk of knee osteoarthrosis (OA) but physically active, were randomly assigned to training program for 12 weeks: with vibration (WBV) and without vibration (CON). The force platforms was used for the strength measurements (Pasco fsample = 500Hz) RESULTS: The data was analiyzed with the software ForceDecks. Statistically significant differences were found for the CON group between Peak Vertical Force (PVF) pre- training: 655N and POST training: 837N (p = 0.00); the rate of force development (RFD) PRE= 935Ns, POST= 1634Ns (p = 0.05), while in the WBV group there was a non- significant increase: PVF (pre-training: 628N and POST training: 685N) (p = 0.29); the RFD (pre-training: 1280Ns and POST training: 1354Ns) (p = 0.57). In the WBV group there was a significant decrease of pain according to the Visual Analogue Scale (VAS). Significant differences were found between the groups being much greater in the group CON, in the isometric leg press test in RFD-200ms (P= 0.03) and relative peak force (P= 0.04). CONCLUSION: In individuals with knee OA 12 weeks of strength training performed with whole body vibration led to lower neuromuscular performance gains than the same training performed without vibration, however pain intensity decreases at knee, hip and lower back level according to the (VAS). Key words: Resistance training, acceleration training, Osteoarthrititis knee, Reflex startle, Muscle strength.