The migratory agriculture (MA) as a direct driver in the dynamics of land use (LU) and land use change (LUC) in the Colombian Andean is evaluated by the spatial and temporal analysis of patterns of change Of cover crops during the periods 1989-1999 and 1999-2008; Where it was identified that the processes of deforestation and fragmentation have been generated by direct causes related to the dominant land uses (monkey potato crop, extensive pastureland) about coverage of natural origin (dense high Andean forest, low Paramo and natural wetland). The LU that presented the largest transformed area were: fragmented forest, pasture cover, potato cultivation, and extensive pasture (79%), low Paramo (78%) and dense Alto Andean forest (80,9%). These LU/LUCs had a direct relationship with spatial factors (elevation, slope, soil fertility, temperature and precipitation), which influenced the dynamics of change or permanence. It was also identified that driving forces such as: public development policies, intensive agriculture, infrastructure improvement, peasant organization, institutional support and armed conflict have streamlined the processes of modification and conversion in the territory mainly those associated with traditional and migratory agriculture; The latter becoming the direct driver of LUC in high Andean ecosystems.