The time-dependent CP asymmetries in B0→π+π− and B0s→K+K− decays are measured using a data sample of p p collisions corresponding to an integrated luminosity of 3.0 fb−1, collected with the LHCb detector at center-of-mass energies of 7 and 8 TeV. The same data sample is used to measure the time-integrated CP asymmetries in B0→K+π− and B0s→π+K− decays. The results are Cπ+π−=−0.34±0.06±0.01, Sπ+π−=−0.63±0.05±0.01, CK+K−=0.20±0.06±0.02, SK+K−=0.18±0.06±0.02, AΔΓK+K−=−0.79±0.07±0.10, AB0CP=−0.084±0.004±0.003, and AB0sCP=0.213±0.015±0.007, where the first uncertainties are statistical and the second systematic. Evidence for CP violation is found in the B0s→K+K− decay for the first time.2 MoreReceived 30 May 2018DOI:https://doi.org/10.1103/PhysRevD.98.032004Published by the American Physical Society under the terms of the Creative Commons Attribution 4.0 International license. Further distribution of this work must maintain attribution to the author(s) and the published article's title, journal citation, and DOI. Funded by SCOAP3.© 2018 CERN, for the LHCb CollaborationPhysics Subject Headings (PhySH)Flavor changing neutral currentsResearch AreasParticle phenomenaParticle interactionsFlavor changing neutral currentsResearch AreasFlavor changing neutral currentsHadronic decaysQuark mixingParticles & Fields